Jean Pouliot| | Professor in Residence, Radiation Oncology Core Member, UCB/UCSF Graduate Group in Bioengineering MtZion Campus: Cancer Center, Dept of radiation Oncology, Office # H1012 mailcode: Box 1708 (415) 353-7190 fax: (415) 353-9883
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http://www.ucsf.edu/jpouliot Membership effective July 2001 |
Research Interests Radiation therapy, brachytherapy, dose optimization algorithm, MV Cone-Beam CT and portal imaging, organ motion and setup study, image-guided therapy Research Summary A major theme for improving radiation therapy is dose conformation, the matching of the high dose irradiated volume to the target volume as closely as possible while avoiding normal tissues. Each of our research projects aims at this goal. My two main thrusts of research interest are on the development and the clinical integration of 1) Dose-Guided Radiation Therapy (DGRT) with Megavoltage Cone-Beam CT (MVCBCT)for patient verification, organ motion and tumor evolution studies during cancer irradiation and 2) an Inverse Planning (IPSA) for the dose distribution optimization and Relative Biological Effectiveness (RBE) of image-guided High Dose-Rate (HDR) and Permanent Prostate Implant (PPI) Brachytherapy. Selected Publications Pouliot J., Bani-Hashemi A., Chen J., Svatos M., Ghelmansarai F., Mitschke M., Aubin M., Xia P., Morin O., Bucci K., Roach III M., Hernandez P., Zheng Z., Hristov D. and Verhey L., D., Low-Dose Megavoltage Cone-Beam CT for Radiation Therapy, Int. J. Radiation Oncology Biol. Phys. 61(2, '); 238-246, 2005. Pouliot, J., Kim, Y., Lessard E., Hsu, I-C. Vigneron D. and Kurhanewicz, J. Inverse Planning For HDR Prostate Brachytherapy Use to Boost Dominant Intra-Prostatic Lesion Defined by Magnetic-Resonance Spectroscopy Imaging. Int. J. Radiation Oncology Biol. Phys.59 (4, '); 1196-1207, 2004 Chen J., Morin O., Aubin M., Bucci M.K., Chuang C.F. and Pouliot J. Dose-Guided Radiation Therapy with Megavoltage Cone-Beam CT, Invited Paper, Br J Radiol 79: S87-S98, 2006. Chen J., Chuang C.F., Morin O., Aubin M. and Pouliot J., Calibration of an amorphous-silicon flat panel portal imager for exit-beam dosimetry. Med. Phys. 33(3, '); 584-594, 2006. Lessard E. and Pouliot J., Inverse Planning Anatomy-based dose optimization for HDR-Brachytherapy of the prostate using fast simulated annealing algorithm and dedicated objective function, Med. Phys. 28 (5), 773-779, 2001.
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