Roland Henry

Research Interests

Development of quantitative techniques for brain imaging. In particular development of diffusion MRI techniques to enable investigation of structure/function relationships in normal brain and neurological disorders.

Research Summary

My research involves quantitative MRI measurements in the brain. These new and exciting techniques yield physiological information about normal and diseased brain. My focus is on the improvement and development of these techniques in order to understand the relevance of these measures and their potential for tissue characterization.

In particular my group has been working on developing diffusion MRI techniques. Diffusion MRI is the only technique that can delineate white matter pathways in the brain. This relatively new technique is growing rapidly in its scope of application and utility in neurological studies.

Selected Publications

RG Henry, JI Berman, S Nagarajan, P Mukherjee, MS Berger. Subcortical Fibers of Speech: DTI Fiber Tracking and Intra-operative Stimulation in Brain Tumor Patients. NeuroImage 21(2, '); 616-622, 2004.

JI Berman, Mukherjee P, Partridge SC, Miller SP, Ferriero DM, Barkovich AJ, Vigneron DB, and Henry RG. Quantitative diffusion tensor MRI fiber tractography of sensorimotor white matter development in premature infants. Neuroimage. 2005 Oct 1;27(4):862-71.

SW Chung, Lu Y, and Henry RG, Comparison of bootstrap approaches for estimation of uncertainties of DTI parameters. NeuroImage 2006 Nov 1;33(2):531-41.

OA Glenn, Ludeman NA, Berman JI, Wu YW, Lu Y, Bartha AI, Vigneron DB, Chung SW, Ferriero DM, Barkovich AJ, Henry RG. Diffusion tensor MR imaging tractography of the pyramidal tracts correlates with clinical motor function in children with congenital hemiparesis. AJNR (2007) 28 (9) pp. 1796-802

JI Berman, Berger MS, Chung SW, Nagarajan SS, Henry RG. Accuracy of diffusion tensor magnetic resonance imaging tractography assessed using intraoperative subcortical stimulation mapping and magnetic source imaging. J Neurosurg. 2007 Sep;107(3):488-94.

SW Chung, Pelletier D, Sdika M, Lu Y, Berman JI, Henry RG. Whole brain voxel-wise analysis of single-subject serial DTI by permutation testing. Neuroimage Epub 2007; (2008) vol. 39 (4) pp. 1693-705.

JI Berman, Chung S, Mukherjee P, Hess CP, Han ET, Henry RG. Probabilistic streamline q-ball tractography using the residual bootstrap. Neuroimage Epub 2007; (2008) vol. 39 (1) pp. 215-22.