Mohammad Mofrad

Mohammad Mofrad

faculty photo

Professor of Bioengineering and Mechanical Engineering

208A Stanley Hall
Mailcode 1762
UC Berkeley

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Research Areas

Biomaterials, Biomechanics, Computational Biology, Bioinformatics, Genomics, Systems & Synthetic Biology, and Tissue Engineering & Regenerative Medicine

Research Interests

Mechanical phenomena affect nearly every aspect of cellular biology and function, yet the underlying mechanisms of how mechanical forces and biochemical signals interact is not clearly understood. The mission of Mofrad Lab’s research program is to understand the regulatory mechanisms involved in mechanotransduction at cellular and subcellular levels, ultimately shedding light on the role of these processes in human disease. Specifically, Mofrad lab is currently engaged in the following projects:

I. Molecular pathways involved in cell mechanotransduction, coupling the extracellular matrix to the nucleus
II. Bacterial mechanotransduction and microbiomes
III. Application of machine learning / deep learning in biology (“deep proteomics” and “deep genomics”) and medicine (“deep medicine”)
IV. Multiscale models of cardiovascular biomechanics, in particular, the aortic valve