Young-Wook Jun

Young-Wook Jun

Associate Professor,
Department of Otolaryngology

2340 Sutter St. #N325
Mailcode 1330
UCSF
415-476-8682
young-wook.jun@ucsf.edu

For more information, see: http://junlab.ucsf.edu/

Research Areas

Biomedical Imaging & Instrumentation, BioMEMS & Nanotechnology, and Neural Systems Engineering & Vision Science
 

Research Interests

My lab focuses on the development of new nanotechnology platforms to study biomolecular dynamics of in vitro and live cell environment. We are developing inorganic colloidal nanoparticle probes with capabilities including i) in vitro magneto-optical force microscopy, ii) tracking of biomolecular diffusion/assembly dynamics, ii) controlling of spatial distributions of target proteins to a desired subcellular location, and iii) regulation of single cell signaling. Specific examples are monovalent quantum dot/plasmonic nanoparticles for monitoring receptor (e.g. Tie2, TrkA) diffusion/assembly dynamics and force-generating magnetoplasmonic nanoparticles for mechanogenetic modulation of spatiotemporal dynamics of cell signaling. I have established an advanced nano-bio research program that broadly investigates these nanoprobing systems for single molecule imaging and in vivo targeting of magnetic nanoparticle probes with high spatiotemporal resolution.