Professor and Chair, Department of Nutritional Sciences and Toxicology
Phone: 510-642-6900
323 Morgan Hall
UC Berkeley
Berkeley, CA 94720-3104
Subject areas:
Research
The overarching goal of our laboratory is to reengineer lipid fluxes in the context of obesity related disorders to protect certain tissues, such as the liver, from detrimental effects of ectopic lipid deposition and to generate metabolically highly active tissues that can serve as a save destination for excess fatty acids. To this end, we are investigating molecular mechanisms governing lipid uptake, particularly for fatty acids and CoQ, hepatobiliary diseases, and adipocyte biology. Toward the later, we have been working on novel bioengineering based approaches to expand and activate brown adipose tissue. Further, to facilitate the assessment of altered nutrient fluxes, we have been developing and testing novel bioluminescent imaging approaches to quantitatively assess macro- and micronutrients in vivo.