January 11, 2012 –
Bioengineering Graduate Group member Professor Sarah Nelson’s lab has new research out on the cover of Science Translational Medicine today.
Bioengineering graduate student Trey Jalbert is co- first author on the publication, which demonstrates the ability to detect the rare metabolite 2HG using magnetic resonance spectroscopic imaging techniques. This biomarker, detectable through non-invasive means, may be able to provide evidence of IDH gene mutations that can help predict survival from some types of cancer.
This new diagnostic could greatly improve the way in which low grade glioma patients are assessed by clinicians and are stratified for the most appropriate therapies or clinical trials. These findings also hold significant importance for other cancers that share these IDH mutations, including prostate cancer and acute myeloid leukemia (AML).
Read the article at Science.